The compositions of the invention are inhibitors of c-myc penoxazone, triazine and pyrazolopyrimidine series relates, more particularly to a pharmaceutical composition for preventing or treating cancer according to a method of manufacturing the same, and this active ingredient. Phenoxazone, triazine series, and pyrazolopyrimidine compounds of the invention may optionally sikimeuroseo stabilize the G-quadruplex structure of c-myc promoter, show the effect of c-myc expression control. This is the development of new anti-cancer DNA target material that exceed the limit of conventional DNA binding anticancer substance, excellent anticancer candidate derived through the optimization of the present invention compounds are c-myc gene is at least wonam induced lung is expressed, result cancer , breast cancer, bladder cancer, can be developed as an anticancer agent for various cancers such as leukemia and is expected to be used in cancer treatment. ; 展开▼