METHOD OF PREDICTING RECOVERY OF VASOREGULATORY FUNCTION OF ENDOTHELIUM IN PATIENTS WITH TYPE 2 DIABETES MELLITUS BY RESULTS OF ENDOTHELIUM-DEPENDENT VASODILATATION ASSESSMENT

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to endocrinology, and can be used for predicting recovery of vasoregulatory function of endothelium in patients with type 2 diabetes mellitus as a result of 6-month long treatment with atorvastatin in 20 mg dose. For this purpose before the beginning of atorvastatin therapy reactive hyperemia test is carried out. After that, assessment of results of endothelium-dependent vasodilatation is performed. For patients with initial endothelium-dependent vasodilatation not less than 8% recovery of vasoregulatory function of endothelium after 6-month long therapy with atorvastatin is predicted.;EFFECT: simple, available, non-invasive method provides possibility of predicting achievement of normal values of endothelium-dependent vasodilatation in patients with type 2 diabetes mellitus, which makes it possible to extend therapeutic possibilities already at early stages of disease, realise complex of preventive measures in due time and prevent development of severe vascular complications in said group of patients.;1 tbl, 2 ex