METHOD OF PREDICTING EFFICIENCY OF RADIOTHERAPY OF MALIGNANT NEOPLASMS OF OROPHARYNGEAL ZONE

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to oncology and radiotherapy, and deals with prediction of efficiency of radiotherapy of malignant neoplasms of oropharyngeal zone. Before treatment index of blood microcirculation I_m and average degree of oxygenation of mixed blood of microcirculature S_tO₂ in tumour are registered. Said indices are used to determine perfusion oxygen saturation, and values of blood microcirculation index I_m' and average degree of oxygenation of mixed blood of microcirculature S_tO₂' in intact zone are measured. Average volume blood filling V_b in tumour and in intact region V_b' are registered, level of activity of oxygen metabolism in cells in examined areas MA, MA' is determined by given formulas. If MA/MA'≥2.5, efficiency of radiotherapy is predicted, if MA/MA'2.5, conclusion about high probability of residual volume of tumour after carrying out radiotherapy is made.;EFFECT: method makes it possible to predict efficiency of tumour regression to impact of distant radiotherapy still at pre-hospital stage, which in its turn contributes to correct and timely selection of method of treatment in accordance with individual plan.;3 ex