A method of predicting REACTION SEVERITY oral mucosa and pharynx DURING radiotherapy or chemoradiotherapy CANCER oropharyngeal

摘要

1.method u043fu0440u043eu0433u043du043eu0437u0438u0440u043eu0432u0430u043du0438u00a0 degree u0442u00a0u0436u0435u0441u0442u0438 reaction of mucous membrane in the oral cavity and oropharynx or u0445u0438u043cu0438u043eu043bu0443u0447u0435u0432u043eu0439 radiation therapy of malignant u043du043eu0432u043eu043eu0431u0440u0430u0437u043eu0432 anius u043eu0440u043eu0444u0430u0440u0438u043du0433u0435u0430u043bu044cu043du043eu0439 area u043eu0442u043bu0438u0447u0430u044eu0449u0438u0439u0441u00a0, prior to radiation therapy or u0445u0438u043cu0438u043eu043bu0443u0447u0435u0432u043eu0439 u043fu0440u043eu0432u043eu0434u00a0u0442 study mucosal cavity method of opt u0438u0447u0435u0441u043au043eu0439 coherent tomography.then in the process of u043bu0435u0447u0435u043du0438u00a0 u043fu0440u043eu0432u043eu0434u00a0u0442 clinical assessment of oral cavity mucous u0441u043eu0441u0442u043eu00a0u043du0438u00a0 daily, before the first clinical signs of radiation u0440u0435u0430u043a u043fu043eu00a0u0432u043bu0435u043du0438u00a0 function in the form of a generally flushing mucous membrane in oral cavity, the first clinical signs of radiation reaction u043fu043eu00a0u0432u043bu0435u043du0438u00a0 day re u043fu0440u043eu0432u043eu0434u00a0u0442 study u043bu0438u0437u0438u0441u0442u043eu0439 lining the oral cavity by optical coherent tomography.the oct image compared with oct - image to u043eu0431u043bu0443u0447u0435u043du0438u00a0 and u043cu0443u043au043eu0437u0438u0442 iii - iv degree predicting missing at the border between the u044du043fu0438u0442u0435u043b oct - image u0438u0435u043c and subject to connective tissue, and u043cu0443u043au043eu0437u0438u0442 i - ii degree for the conservation of this border.;2. method for u043eu0442u043bu0438u0447u0430u044eu0449u0438u0439u0441u00a0 1, so that the clinical assessment of oral cavity mucous u0441u043eu0441u0442u043eu00a0u043du0438u00a0 u043fu0440u043eu0432u043eu0434u00a0u0442 in accordance with the classification of u0441u0442u0441u0430u0435.;3. method for u043eu0442u043bu0438u0447u0430u044eu0449u0438u0439u0441u00a0 1, so that the first clinical signs of radiation response of oral mucosa is usually observed at the 6 - 9 day u043eu0431u043bu0443u0447u0435u043du0438u00a0.;4. method for u043eu0442u043bu0438u0447u0430u044eu0449u0438u0439u0441u00a0 1, so that the study of oral mucosa by optical coherent tomography u043fu0440u043eu0432u043eu0434u00a0u0442 at any point of the cheeks. u043au043eu0442u043eu0440u0430u00a0 hits the u043eu0431u043bu0443u0447u0435u043du0438u00a0, but at the same time, both u0438u0441u0441u043bu0435u0434u043eu0432u0430u043du0438u00a0 u043fu0440u043eu0432u043eu0434u00a0u0442u0441u00a0 in one and the same point.;5. method for u043eu0442u043bu0438u0447u0430u044eu0449u0438u0439u0441u00a0 p.4, however, preferred u00a0u0432u043bu00a0u0435u0442u0441u00a0 choice point on the cheek in the middle of the line, u0441u043eu0435u0434u0438u043du00a0u044eu0449u0435u0439 corner of mouth and the mouth of a salivary duct ductless glands.