首页> 外国专利> Nasal preparation, used to topical, protective, nurturing/supporting application to treat irritation/swelling in nasal mucosa due to e.g. allergies, includes mineral salt, water, alcohols, poloxamer surfactants, and additives e.g. enzyme

Nasal preparation, used to topical, protective, nurturing/supporting application to treat irritation/swelling in nasal mucosa due to e.g. allergies, includes mineral salt, water, alcohols, poloxamer surfactants, and additives e.g. enzyme

机译:鼻用制剂,用于局部,保护性,养育/支持性应用,以治疗例如由于鼻粘膜引起的鼻粘膜的刺激​​/肿胀。过敏,包括矿物质盐,水,酒精,泊洛沙姆表面活性剂和添加剂,例如酵素

摘要

Nasal preparation comprises: 0.5-4 wt.% of mineral salt having at least 70 wt.%, based on the salt mixture, of sodium chloride salt as a main active ingredient comprising table salt, rock salt and sea salt different origin; 56.5-84.5 wt.% of water; 6-20 wt.% of one or more alcohols comprising ethylene glycol, propylene glycol and/or glycerol; 6-20 wt.% of one or more poloxamer surfactants (polyoxyethylene-polyoxypropylene block polymers) with an average molar mass of 1800-18000 g/mole; and 0-5 wt.% of additives, where a weight ratio of the poloxamers and the alcohol is 1.3:1-1:1. Nasal preparation comprises: 0.5-4 wt.% of mineral salt having at least 70 wt.%, based on the salt mixture, of sodium chloride salt as a main active ingredient comprising table salt, rock salt and sea salt different origin; 56.5-84.5 wt.% of water; 6-20 wt.% of one or more alcohols comprising ethylene glycol, propylene glycol and/or glycerol; 6-20 wt.% of one or more poloxamer surfactants (polyoxyethylene-polyoxypropylene block polymers) with an average molar mass of 1800-18000 g/mole; and 0-5 wt.% of additives comprising essential oils, water-soluble vitamins, enzymes, proteins and zinc salts, other H-regulators, preserving agents, and/or consistency agents, where a weight ratio of the poloxamers and the alcohol is 1.3:1-1:1. An independent claim is included for spay- or spray applicator comprising 10-100 ml of the preparation.
机译:鼻用制剂包含:0.5-4重量%的矿物盐,基于盐混合物,其具有至少70重量%的氯化钠盐作为主要活性成分,其包含不同来源的食盐,岩盐和海盐;和56.5-84.5 wt。%的水; 6-20重量%的一种或多种包含乙二醇,丙二醇和/或甘油的醇; 6-20重量%的一种或多种泊洛沙姆表面活性剂(聚氧乙烯-聚氧丙烯嵌段聚合物),平均摩尔质量为1800-18000g / mol;和0-5重量%的添加剂,其中泊洛沙姆与醇的重量比为1.3:1-1:1。鼻用制剂包含:0.5-4重量%的矿物盐,基于盐混合物,其具有至少70重量%的氯化钠盐作为主要活性成分,其包含不同来源的食盐,岩盐和海盐;和56.5-84.5 wt。%的水; 6-20重量%的一种或多种包含乙二醇,丙二醇和/或甘油的醇; 6-20重量%的一种或多种泊洛沙姆表面活性剂(聚氧乙烯-聚氧丙烯嵌段聚合物),平均摩尔质量为1800-18000g / mol;和0-5 wt。%的添加剂,包括精油,水溶性维生素,酶,蛋白质和锌盐,其他H调节剂,防腐剂和/或稠度剂,其中泊洛沙姆和醇的重量比为1.3:1-1:1。对于包含10-100 ml制剂的喷雾或喷雾器,包括独立权利要求。

著录项

  • 公开/公告号DE102013001151A1

    专利类型

  • 公开/公告日2014-07-24

    原文格式PDF

  • 申请/专利权人 MERZ PHARMA GMBH & CO. KGAA;

    申请/专利号DE20131001151

  • 发明设计人 BERLEKAMP UWE;MÖHLE MELANIE;

    申请日2013-01-24

  • 分类号A61K33/14;A61K31/047;A61K38/43;A61K33/30;A61P11/02;A61P37/08;A61K31/765;A61K36;

  • 国家 DE

  • 入库时间 2022-08-21 15:37:32

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