To contrast the lymph nodes by using this based on the iron oxide nanoparticles lymphography for MRI contrast agents and how

摘要

Contrast agent intended for lymph node imaging, including the iron oxide nanoparticles dispersed stabilized by mussel adhesive protein mimics copolymer to disperse in an aqueous solvent in the nanoparticles and the present invention, lymph node using this relates to a method for the imaging. To prepare a colloidal solution and dispersed uniformly in water with the modified iron oxide surface using the mussel adhesive protein mimics copolymer, to prepare contrast agents containing the same. Not toxic, shows a lymph node imaging excellent effect is easily deposited in the lymph nodes, this contrast agent is useful in the diagnosis of metastatic cancer. [Selection] Figure Figure 1