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IGF1 BIOMARKER FOR IGF1R INHIBITOR THERAPY
IGF1 BIOMARKER FOR IGF1R INHIBITOR THERAPY
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机译:用于IGF1R抑制剂治疗的IGF1生物标志物
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摘要
The present invention provides, inter alia, methods for treating tumors that are sensitive to an IGF1R inhibitor. The tumor are determined to be sensitive if the level of IGF1 mRNA expression in the tumor cells, relative to one or more reference genes, reaches a certain threshold level. Methods for evaluating patients as candidates for receipt of the IGF1R inhibitor therapy are also provided as well along with in vitro assay methods and kits for performing any of the methods.
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