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METHODS TO REDUCE POLYPOSIS AND COLORECTAL CANCER
METHODS TO REDUCE POLYPOSIS AND COLORECTAL CANCER
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机译:减少息肉和大肠癌的方法
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摘要
Methods for reducing or inhibiting polyposis or colorectal cancer are provided. The methods comprise administering to a mammal a bacterium modified to decrease the display of lipoteichoic acid on the cell surface. Administration of the recombinant bacterium promotes a desired therapeutic response. The recombinant bacterium may be administered in a single dose or series of doses. Methods find use in treating or preventing a variety of polyp-related disorders, for example, treating or Lynch syndrome, familial adenomatous polyposis, and colorectal cancer.
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