首页> 外国专利> ABSORPTION ENHANCERS SUCH AS E.G. BHT, BHA OR PROPYL GALLATE

ABSORPTION ENHANCERS SUCH AS E.G. BHT, BHA OR PROPYL GALLATE

机译:吸收增强剂,例如BHT,BHA或没食子酸丙酯

摘要

The invention provides a pharmaceutical composition comprising a mixture of (a) an active macromolecular principle, and (b) an aromatic alcohol absorption enhancer chosen from butylated hydroxy toluene, butylated hydroxy anisole and analogues and derivatives thereof, wherein the aromatic alcohol absorption enhancer is present in an amount by weight greater than or equal to that of the active macromolecular principle, and further comprises a pharmaceutical composition comprising a mixture of (a) an active macromolecular principle, (b) an aromatic alcohol absorption enhancer chosen from propyl gallate, butylated hydroxy toluene, butylated hydroxy anisole and analogues and derivatives thereof, wherein the aromatic alcohol absorption enhancer is present in an amount by weight greater than or equal to that of the active macromolecular principle, and (c) a solubilisation aid capable of increasing the solubility of the aromatic alcohol absorption enhancer in aqueous media.
机译:本发明提供了药物组合物,其包含(a)活性大分子原理和(b)选自丁基化羟基甲苯,丁基化羟基茴香醚及其类似物和衍生物的芳族醇吸收增强剂的混合物,其中存在芳族醇吸收增强剂的量按重量计大于或等于活性大分子原理的量,并且还包含药物组合物,该药物组合物包含(a)活性大分子原理的混合物,(b)选自没食子酸丙酯,丁基化羟基的芳族醇吸收增强剂甲苯,丁基化羟基茴香醚及其类似物和衍生物,其中芳族醇吸收促进剂的存在量按重量计大于或等于活性大分子原理的量,和(c)能够增加溶剂的溶解度的助溶剂在水性介质中的芳香醇吸收增强剂。

著录项

  • 公开/公告号US2015093419A1

    专利类型

  • 公开/公告日2015-04-02

    原文格式PDF

  • 申请/专利权人 AXCESS LIMITED;

    申请/专利号US201414559963

  • 发明设计人 ROGER R.C. NEW;

    申请日2014-12-04

  • 分类号A61K47/10;A61K47/28;A61K47/14;

  • 国家 US

  • 入库时间 2022-08-21 15:22:25

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