The side effect of risk assessment is the use of drugs.

摘要

The present invention provides a risk to the development of predictive methods of adverse drug reactions to a patient's use, in particular Syndrome (SJS), toxic epidermal necrolysis (10), or drug allergy syndrome (translation).A allele HLA - 13, HLA-B * 1502 SJS / TEN was found to be involved in a variety of drugs. The associated HLA-B * 1502, more importantly, was examined in patients with SJS / TEN carbamazepine by examining the - 13 * 1502 HLA allele.In addition, another allele, HLA-13, HLA-B*5801, is involved especially in translational SJS/10 or allopurinol-induced. Mild skin reactions, such as maculopapular rash, erythema multiforme (UM), urticaria, drug eruption, and stabilization, especially_delta Delta Delta Delta Delta Delta Delta Delta Delta Delta Delta Delta Delta Delta Delta Delta Delta Delta Delta Delta_Delta Third alleles and HLA 13 x 4601.For all alleles, it can also be used for testing (e.g. genetic markers). _______HLA polymorphism indicators, indicators or indicators between the_____located in the HLA DRB1 and A region A special a___HLA-B.