NOVEL MULTICOMPONENT CRYSTALS MADE OF (2-AMINO-6-(4-FLUORO-BENZYLAMINO)PYRIDIN-3-YLCARBAMIC ACID ETHYL ESTER AND 2-2-(2,6-DICHLORPHENYL)AMINOPHENYLACETIC ACID

摘要

The invention relates to novel multicomponent crystals, to the production thereof, and to the use thereof for treating pain conditions, in particular of unclear genesis, by means of a simultaneous effect on pains which are caused by muscle tension or degenerative joint diseases as well as on pains that are based on inflammatory processes. The novel multicomponent crystals contain ([2-amino-6-(4-fluoro-benzylamino)pyridin-3-yl]carbamic acid ethyl ester (flupirtine) and 2-[2-[(2,6-dichlorphenyl)amino]phenyl]acetic acid (diclofenac) as the sole active ingredient combination and can be produced by dissolving the two components in a molar ratio of 1.0:0.9 to 1.0:1.1 in an inert organic solvent and subsequently crystallizing the complex compound.