Piperazino 1,2-a indole - 3 - onas and 1,4 diazepino 1,2-a indole - 3 - ona

摘要

The Invention relates to compounds of the General formula I: wherein R1 is Hydrogen, halogen, etc. R2 is Hydrogen, Lower alkyl or lower alkyl phenyl substituted by Halogen; R3 is, etc.X is - ch (Lower alkyl) -, - CH2 -, - or - ch2ch2 - CH2 CH (Lower alkyl) -; R is Hydrogen or lower alkyl; n is 1 or 2; or a pharmaceutically acceptable acid Addition Salt, its enantiomer or a racemic mixture and / or their isomers Optical.Preferred compounds are: (R) - 6 - (4 - methoxy phenyl) - 4 - methyl - 3,4-dihydro - 2H - pirazino [1,2-a] indole - 3 - One; (R) - 8 - fluor - 4 - methyl - 4 - phenyl - 3,4-dihydro - 2H - pirazino [1,2-a] - indole - 3 - One; (R) - 8 - fluor - 6 - (4 - methoxy phenyl) - 4 - methyl - 3,4-dihydro - 2H - pirazino [1,2-a] indole - 3 - One; the compounds can be used to The Treatment of schizophrenia, obsessive-compulsive Personality Disorder, among others