Method for obtaining useful data predict or forecast the response to treatment with standard combination therapy (pegylated interferon plus ribavirin) in patients with chronic hepatitis C genotype 1 (HCC-G1)

摘要

Method of obtaining useful to predict or forecast the response to treatment with standard combination therapy (pegylated interferon plus ribavirin) in patients with chronic hepatitis C genotype 1 (HCC-G1) data. # The present invention relates to a method of obtaining data useful in predicting or prognosing the response to treatment with pegylated interferon plus ribavirin in chronic hepatitis C genotype 1 (HCC-G1), combining several predictors: levels of IP-10, basal cortisol, genetic polymorphism of the Interleukin 28B (IL28B ), creatine clearance, 2 viral load (HCV RNA) and 5 determinations of lipoproteins: LDL-cholesterol, HDL-cholesterol and triglycerides. Furthermore, the present invention discloses the kit to predict or forecast the response to pegylated interferon plus ribavirin in chronic hepatitis C genotype 1 (HCC-G1) as shown in the present invention and its different uses.