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PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DEGENERATIVE CRANIAL NERVE DISEASES

机译:预防或治疗变性颅神经疾病的药物组合物

摘要

The present invention relates to a composition for alleviating oxidative stress-induced cranial nervous system diseases, containing corn silk-derived maysin as an active ingredient and, more particularly, to a pharmacological composition for alleviating degenerative cranial nervous system diseases, wherein maysin increases the expression of mRNAs of antioxidant enzymes (catalase, glutathione peroxidase-1, superoxide dismutases 1 and 2, and heme oxygenase-1), thereby decreasing oxidative stress, and ultimately, inhibiting or blocking nerve cell apoptosis caused by oxidative stress.
机译:本发明涉及用于减轻氧化应激诱导的颅神经系统疾病的组合物,其包含玉米丝来源的maysin作为活性成分,更具体地,涉及用于减轻变性的颅神经系统疾病的药理组合物,其中maysin增加表达。抗氧化酶(过氧化氢酶,谷胱甘肽过氧化物酶-1,超氧化物歧化酶1和2和血红素加氧酶-1)的mRNA表达,从而降低氧化应激,并最终抑制或阻断由氧化应激引起的神经细胞凋亡。

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