ENDOTHELIAL CELLS ACTIVATION BIOMARKERS CHARACTERIZING ANTIBODY MEDIATED REJECTION AND USES THEREOF

摘要

Described herein are methods and kits for the detection of endothelial cell injury and/or activation and to the diagnostic of transplant antibody mediated rejection (ABMR). The invention further relates to methods and kits for diagnosing endothelial to mesenchymal transition (EndMT). In various embodiments, the methods comprise assessing expression of one, two or three biomarkers selected from Fascin1, Vimentin and Hsp47.