The present invention relates to a novel cytomegalovirus (CMV) infection model and a method for diagnosing true CMV infection by using the same. When a two-dimensional CMV infection model is applied, an innocent bystander can be distinguished from true infection in an actual clinical case. Therefore, an innocent bystander patient can be less exposed to ganciclovir, an antivirus agent which is highly toxic, and ganciclovir can be properly injected into a patient with true infection. Consequently, prognosis of the patient can be improved.
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