CRYSTALLINE (6R,7R)-7-｛2-(5-AMINO-1,2,4THIADIAZOL-3-YL)-2-(Z)-TRITYLOXYIMINO-ACETYLAMINO｝-3-(R)-1'-TERT-BUTOXYCARBONYL-2-OXO-1,3'BIPYRROLIDINYL-(3E)-YLIDENEMETHYL-8-OXO-5-THIA-1-AZA-BICYCLO4.2.0OCT-2-ENE-2-CARBOXYLIC ACID BENZHYDRYL ESTER； ITS MANUFACTURE AND USE

摘要

A solid DMSO solvate of a compound of formula (I) is described, which is a useful intermediate for preparing the broad spectrum antibiotics Ceftobiprole and Ceftobiprole Medocaril.