Synthesis, spectroscopy and X-​ray crystal structure of 9-​methyl-​3-​(2-​thienyl)​thieno3,​2-​e​1,​2,​4​triazolo4,​3-​c​pyrimidine-​8-​carboxylic acid ethyl ester

摘要

The synthesis of the target compd. was achieved by a reaction of 4-​cyano-​5-​[(ethoxymethylene)​amino]​-​3-​methyl-​2-​thiophenecarboxylic acid Et ester with 2-​thiophenecarboxylic acid hydrazide. The product thus obtained was confirmed by elemental anal., IR, 1H-​NMR, 13C-​NMR and X-​ray crystal structure anal. [i.e., 9-​methyl-​3-​(2-​thienyl)​thieno[3,​2-​e]​-​1,​2,​4-​triazolo[4,​3-​c]​pyrimidine-​8-​carboxylic acid Et ester]​. There are two independent mols. in the asym. unit exhibiting intermol. C-​H...N, C-​H...O interactions with addnl. π-​π interaction that further helps in stabilizing the supramol. structure.