首页> 外国专利> PHARMACEUTICAL COMPOSITION, INCLUDING AN AMIDA DERIVATIVE, INHIBITING CANCER CELL GROWTH, AND A LUBRICANT, NOT A METAL SALT

PHARMACEUTICAL COMPOSITION, INCLUDING AN AMIDA DERIVATIVE, INHIBITING CANCER CELL GROWTH, AND A LUBRICANT, NOT A METAL SALT

机译:药物成分,包括酰胺衍生物,抑制癌细胞的生长和润滑剂而不是金属盐

摘要

1. A pharmaceutical composition comprising a substance of formula (I) or a pharmaceutically acceptable salt thereof and a non-metal lubricant: 2. The pharmaceutical composition according to claim 1, wherein the claimed non-metal lubricant is selected from the group consisting of fatty acid esters, fatty acids, fatty alcohols, oils, fumaric acid, polyethylene glycols (PEGs), talc and mixtures thereof. 3. The pharmaceutical composition of claim 2, wherein the claimed non-metal salt lubricant is selected from the group consisting of glyceryl behenate, glyceryl palmitostearate, glyceryl monostearate, glyceryl trimyristate, glyceryl tristearate, sucrose and fatty acid ester, palmitic acid, palmitic acid, palmitic acid, palmitic acid, palmitic acid acid, stearyl alcohol, hydrogenated castor oil, mineral oil, hydrogenated vegetable oil, fumaric acid; PEG 4000, PEG 6000; polytetrafluoroethylene; starch, talc and mixtures thereof. 4. The pharmaceutical composition of claim 3, wherein the claimed non-metal lubricant is a sucrose and fatty acid ester or hydrogenated vegetable oil. The pharmaceutical composition according to claim 1, wherein the claimed substance of formula (I) is contained in an amount in the range from 0.1 mg to 100 mg per 1 dosage unit of the composition. The pharmaceutical composition of claim 1, wherein the claimed non-metal lubricant is contained in an amount in the range of 0.1 to 100 parts by weight based on 1 part by weight of the compound of formula (I). 7. The pharmaceutical composition according to claim 1, further comprising a pharmaceutically acceptable additive selected from the group consisting of a diluent,
机译:1.包含式(I)的物质或其药学上可接受的盐和非金属润滑剂的药物组合物:2.根据权利要求1的药物组合物,其中所要求保护的非金属润滑剂选自下组:脂肪酸酯,脂肪酸,脂肪醇,油,富马酸,聚乙二醇(PEG),滑石粉及其混合物。 3.权利要求2的药物组合物,其中所要求保护的非金属盐润滑剂选自山酸甘油酯,棕榈硬脂酸甘油酯,单硬脂酸甘油酯,偏苯三酸甘油酯,三硬脂酸甘油酯,蔗糖和脂肪酸酯,棕榈酸,棕榈酸,棕榈酸,棕榈酸,棕榈酸,硬脂醇,氢化蓖麻油,矿物油,氢化植物油,富马酸; PEG 4000,PEG 6000;聚四氟乙烯淀粉,滑石粉及其混合物。 4.权利要求3的药物组合物,其中要求保护的非金属润滑剂是蔗糖和脂肪酸酯或氢化植物油。 2.根据权利要求1的药物组合物,其中每1剂量单位的组合物包含的所要求的式(I)物质的量为0.1mg至100mg。 2.权利要求1的药物组合物,其中基于1重量份的式(I)化合物,所要求保护的非金属润滑剂的含量在0.1至100重量份的范围内。 7.根据权利要求1的药物组合物,进一步包含选自稀释剂的药学上可接受的添加剂,

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