A synthesized butyrolactone derivative in combination with chloroquine can inhibit cancer cell growth and lysosome vacuolation induced by chloroquine in A549 lung cancer cells

Xin-Peng Chen; Chuan-Dong Fan; Le Su; Bao-Xiang Zhao; Jun-Ying Miao

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A synthesized butyrolactone derivative in combination with chloroquine can inhibit cancer cell growth and lysosome vacuolation induced by chloroquine in A549 lung cancer cells

机译：合成的丁内酯衍生物与氯喹组合可以抑制A549肺癌细胞中氯喹菌诱导的癌细胞生长和溶酶体真空

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3BDO in combination with chloroquine could elevate the Na ~(+) ,K ~(+) -ATPase activity and decrease the expression of long non-coding RNA TGFB2-OT1 . Therefore, the combination inhibited the cell growth and lysosomal vacuolation.

机译：3BDO与氯喹组合可以升高Na〜（+），K〜（+）-ATP酶活性，并降低长非编码RNA TGFB2-OT1的表达。因此，该联合抑制细胞生长和溶酶体真空。

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《RSC Advances》 |2016年第59期|共3页
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Xin-Peng Chen; Chuan-Dong Fan; Le Su; Bao-Xiang Zhao; Jun-Ying Miao;
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1. A synthesized butyrolactone derivative in combination with chloroquine can inhibit cancer cell growth and lysosome vacuolation induced by chloroquine in A549 lung cancer cells [J] . Chen Xin-Peng, Fan Chuan-Dong, Su Le, RSC Advances . 2016,第59期

机译：合成的丁内酯衍生物与氯喹组合可以抑制A549肺癌细胞中氯喹菌诱导的癌细胞生长和溶酶体真空
2. Chloroquine inhibits cell growth and induces cell death in A549 lung cancer cells. [J] . Fan C, Wang W, Zhao B, Bioorganic and Medicinal Chemistry . 2006,第9期

机译：氯喹在A549肺癌细胞中抑制细胞生长并诱导细胞死亡。
3. Chloroquine inhibits cell growth in human A549 lung cancer cells by blocking autophagy and inducing mitochondrial-mediated apoptosis [J] . Liu Likun, Han Cuicui, Yu Haitao, Oncology reports . 2018,第6期

机译：通过阻断自噬和诱导线粒体介导的细胞凋亡，氯喹抑制人A549肺癌细胞中的细胞生长
4. The effect of chloroquine on the apoptosis induced by cisplatin in human gastric cancer BGC823 cells [C] . Zhenxun Jin, Lili Zhang, Yan Wang, International Conference on Materials Science and Computational Engineering . 2014

机译：氯喹对人胃癌BGC823细胞顺铂诱导凋亡的影响
5. Mirna-143/506 Induces Cell Cycle Arrest and Inhibits Tumor Growth Using a Novel Nanocarrier in Lung Cancer [D] . Hossian, A. K. M. Nawshad. 2020

机译：miRNA-143/506诱导细胞周期停滞并使用肺癌中的新纳米载体抑制肿瘤生长
6. Chloroquine increases the anti-cancer activity of epirubicin in A549 lung cancer cells [O] . Ai-Ling Liang, Jing Zhang, Shen-Lin Du, -1

机译：氯喹增强表柔比星在A549肺癌细胞中的抗癌活性
7. Chloroquine increases the anti‑cancer activity of epirubicin in A549 lung cancer cells [O] . Ai‑Ling Liang, Jing Zhang, Shen‑Lin Du, 2020

机译：氯喹增加了A549肺癌细胞中表皮蛋白的抗癌活性

A synthesized butyrolactone derivative in combination with chloroquine can inhibit cancer cell growth and lysosome vacuolation induced by chloroquine in A549 lung cancer cells

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