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PTHRP, ITS ISOFORMS AND ANTAGONIST THERETO IN THE DIAGNOSIS AND TREATMENT OF DISEASE

机译：PTHRP，其同工型及其拮抗剂在疾病诊断和治疗中的作用

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摘要

The present invention is directed to the use of an effective amount of an isolated antibody that specifically binds an N-terminal portion of one or more PTHrP isoforms or a C-terminal portion of the PTHrP 1-173 isoform for inhibiting the growth and metastatis of cancer cells, more preferably wherein the antibody is a monoclonal antibody.

机译：本发明针对有效结合一种或多种PTHrP 1-173同工型的N-末端部分或PTHrP 1-173同工型的C-末端部分的分离抗体，以抑制其生长和转移的用途。癌细胞，更优选其中抗体是单克隆抗体。

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公开/公告号EP2190990B1

专利类型
公开/公告日2016-02-17

原文格式PDF
申请/专利权人 BIOCHROM PHARMA INC.;
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申请/专利号EP20080783388
发明设计人 KREMER RICHARD;HUANG DAO CHAO;
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申请日2008-08-18
分类号C12N15/11;A61K31/713;A61K48;A61K49/16;A61K51/10;A61P35;C07K16/26;C12N15/12;C12N15/16;C12N5/16;C07K14/635;C12P21/08;
国家 EP
入库时间 2022-08-21 14:51:23

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