Tablets containing candesartan cilexetil and hydrochlorothiazide

摘要

[Problem] in the formulation tablet comprising candesartan cilexetil and hydrochlorothiazide, it can be realized and the suppression of the generation of related substances, and improvement of tablet hardness. And A candesartan cilexetil, and hydrochlorothiazide, and a water-soluble polymer or ester compound, tablets containing the mixture tablet molding of a granular composition comprising a candesartan cilexetil containing granules and hydrochlorothiazide-containing granules to get. Alternatively, in the tablet, the content of water-soluble polymer or an ester compound, and less than 2wt / wt% based on the weight of the tablet.BACKGROUND