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Compounds and methods for the treatment of Alzheimer's disease and familial dementia
Compounds and methods for the treatment of Alzheimer's disease and familial dementia
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机译:用于治疗阿尔茨海默氏病和家族性痴呆的化合物和方法
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摘要
An isolated protein is provided for use in treatment of a condition selected from the group consisting of Alzheimer's disease, familial Danish dementia and familial British dementia in a mammal, including man. The isolated protein is selected from the group consisting of proteins comprising an amino acid sequence having at least 70% identity to residues 90-236 of Bri2 from human; and proteins comprising an amino acid sequence having at least 70% identity to any one of the Brichos domains of Bri2 from human, chimpanzee, bovine, pig, mouse and rat.
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