Recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma
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机译:EBV相关鼻咽癌的复发性转化UBR5-ZNF423融合基因
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摘要
The present invention provides a method for diagnosing nasopharyngeal cancer in a subject by detecting UBR5-ZNF423 fusion polypeptide or polynucleotide, which is in some cases due to a gene fusion of UBR5-ZNF423. A kit useful for such a method is also provided. In addition, the present invention provides a method for treating nasopharyngeal cancer by eliminating UBR5-ZNF423 gene expression or activity.
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