首页> 外国专利> 'purified compound, purified or partially purified bacterial extract, pharmaceutical composition, methods for treating or preventing bacterial infection in a mammalian subject and for controlling bacterial infection in a mammalian individual, biologically pure culture, and process for preparing the composition'

'purified compound, purified or partially purified bacterial extract, pharmaceutical composition, methods for treating or preventing bacterial infection in a mammalian subject and for controlling bacterial infection in a mammalian individual, biologically pure culture, and process for preparing the composition'

机译:“纯化的化合物,纯化的或部分纯化的细菌提取物,药物组合物,在哺乳动物个体中治疗或预防细菌感染和控制细菌感染的方法,生物纯净的培养物以及制备该组合物的方法”

摘要

"purified compound, purified or partially purified bacterial extract, pharmaceutical composition, methods for treating or preventing bacterial infection in a mammalian subject and for controlling bacterial infection in a mammalian subject, biologically pure culture, and process for preparing the composition" The present invention relates to novel compounds of formulas (i) and (ii), and pharmaceutically acceptable salts thereof, which are used in the treatment and / or prevention of bacterial infections in humans and animals, and associated conditions and diseases; compositions containing such compounds; derivation of such compounds by fermentation and isolation, partial synthesis and total synthesis; method for inhibiting bacterial growth; methods for treating, preventing or controlling bacterial infection; biologically pure cultures of bacterial strains from which such compounds may be produced; and processes for preparing compositions containing such compounds.
机译:本发明涉及“纯化的化合物,纯化或部分纯化的细菌提取物,药物组合物,在哺乳动物受试者中治疗或预防细菌感染并在哺乳动物受试者中控制细菌感染的方法,生物学上纯净的培养物以及制备该组合物的方法”涉及式(i)和(ii)的新型化合物及其药学上可接受的盐,其用于治疗和/或预防人和动物的细菌感染以及相关的状况和疾病;含有这类化合物的组合物;通过发酵和分离,部分合成和全合成得到这类化合物;抑制细菌生长的方法;治疗,预防或控制细菌感染的方法;可以从中生产此类化合物的细菌菌株的纯生物培养物;和制备含有这种化合物的组合物的方法。

著录项

  • 公开/公告号BR112012015177A2

    专利类型

  • 公开/公告日2016-03-29

    原文格式PDF

  • 申请/专利权人 MERCK SHARP & DOHME CORP.;

    申请/专利号BR20121115177

  • 发明设计人 SHEO S. SINGH;

    申请日2010-12-17

  • 分类号C07D407/14;A61K31/4025;A61K31/5355;A61P31;C07D413/14;C12N1;

  • 国家 BR

  • 入库时间 2022-08-21 14:27:25

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