administration of an anti-obesity compound to individuals with renal impairment

摘要

administration of an anti-obesity compound to individuals with renal impairment. The present disclosure relates to weight control in an individual in need thereof by determining the subject's renal sufficiency level and the prescription or administration of a therapeutically effective amount of (r) -8-chloro-1-methyl-2, 3,4,5-tetrahydro-1h-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof to the subject, provided that the subject has a selected renal sufficiency level from the group consisting of: no renal impairment, renal impairment and moderate renal impairment. furthermore, the description relates to a method for selecting an individual for treatment with (r) -8-chloro-1-methyl-2,3,4,5-tetraido-1h-3-benzazepine or a pharmaceutically salt thereof acceptable, solvate or hydrate thereof from a plurality of subjects in need of weight control by determining the individual's renal sufficiency level and selecting the subject for treatment with (r) -8-chloro-1-methyl-2,3, 4,5-Tetrahydro-1h-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof if the individual has a renal sufficiency level selected from the group consisting of: no renal impairment, mild renal impairment and moderate renal impairment .