FINE DRY COMPOSITIONS OF RETINOID ACTIVE MEANS AND CONTAINING THEIR COMPOSITIONS FOR LOCAL APPLICATION

摘要

There are fine dry retinoid compositions suitable for use in topical formulations, as well as methods for their preparation. In dry particulate retinoid compositions, the retinoid active agent is bound to the particles, for example, by holding the particles in the pores and / or forming an ionic bond, and / or forming a non-covalent bond with the surface of the particles and / or weakly bonding with the particles. Topical formulations are also contemplated, which include dry dispersion retinoid compositions according to the present invention, and methods for their use.