SYNERGISTIC POLY-HERBAL COMPOSITION FOR INHIBITING PROLIFERATION OF CANCER CELLS BY INDUCING PROGRAMMED CELL DEATH

摘要

ABSTRACT The present invention relates to a synergistic poly-herbal composition for inhibiting proliferation of Cancer cells by inducing programmed cell death. To achieve the synergistic poly-herbal composition, extract of a portion of plant Trichopus zeylanicus, extract of a portion of plant Cissus quadrangularis, extract of a portion of plant Andragraphis paniculata, being in the range of half the weight of Trichopus zeylanicus and Cissus quadrangularis are shade dried and their extract is subjected to fermentation after soaking in quality control (QC) approved food grade solution. The medicinal effect of the said composition is achieved by the bioactive components of the above said plants. Said synergistic poly-herbal composition eliminates 50 % of cancerous cells in cellular material in a time duration of 24 hours. Said composition has excellent anti cancer activity at the concentration of 10ul to induce Apoptosis and Necrosis in colon carcinoma cell line and is a therapeutic agent. [Figure to be accompanied with Abstract: Figure 9(b) & Figure 9(c)]