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ISOLATION AND CHARACTERIZATION OF ACTIVE CONSTITUENT FROM TYLOPHORA PAUCIFLORA, BEING A COMPONENT FOR THE TREATMENT OF PROSTATE CANCER
ISOLATION AND CHARACTERIZATION OF ACTIVE CONSTITUENT FROM TYLOPHORA PAUCIFLORA, BEING A COMPONENT FOR THE TREATMENT OF PROSTATE CANCER
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机译:圆柏中有效成分的分离和鉴定,是前列腺癌治疗的成分
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摘要
A process for isolating and identifying the active constituent of ethanolic extract of Tylophora pauciflora, being a constituent for the treatment of ovarian cancer, comprising the steps, in combination, of subjecting samples of the said extract to Column chromatography and Thin layer column chromatography for the separation of active constituents; Fourier transforms infrared (FTIR) spectroscopy for analysis of the phytoconstituents functional groups for identifying the functional groups; identification of the structure of the active constituents by Nuclear Magnetic Resonance (NMR) spectroscopy: two dimensional nuclear magnetic resonance (2D NMR) spectroscopy for resolving and identifying the nature of chemical sites in the sample; HSQC (Heteronuclear Single Quantum Coherence) for the detection of bond couplings; H - H COSY (Homonuclear Correlation Spectroscopy) for revealing correlations between coupled protons; the overall analysis indicating a structure of the active constituent of the said extract with a molecular formula = Ctb molecular weight equal to 226.44 grams / mole, compound name: Hexadecane.
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