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USE OF THE COMBINATION OF AN INHIBITOR OF THE IF CURRENT OF THE SINOATRIAL NODE AND AN INHIBITOR OF THE ANGIOTENSIN-CONVERTING ENZYME FOR TREATING HEART FAILURE
USE OF THE COMBINATION OF AN INHIBITOR OF THE IF CURRENT OF THE SINOATRIAL NODE AND AN INHIBITOR OF THE ANGIOTENSIN-CONVERTING ENZYME FOR TREATING HEART FAILURE
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机译:窦房结IF电流抑制剂和血管紧张素转化酶抑制剂治疗心力衰竭的组合
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摘要
Combination (I) comprises a selective and specific sinusal I f(mixed sodium ion-potassium ion inward current) current inhibitor (A) and an angiotensin converting enzyme inhibitor (B). An independent claim is included for pharmaceutical compositions comprising: ivabradine, in the form of hydrochloride or its hydrate or crystalline forms, and perindopril, in the form of salt of tert-butylamine or arginine or their hydrates or crystalline forms, alone or in combination with one or more excipient. ACTIVITY : Cardiant; Cardiovascular-Gen.; Vasotropic; Antianginal; Antiarrhythmic. MECHANISM OF ACTION : Sinusal I fcurrent inhibitor; Angiotensin converting enzyme inhibitor.
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