Genetic markers of efficacy of iloperidone in the treatment of psychotic symptoms

摘要

A method of predicting the efficacy of iloperidone or a pharmaceutically acceptable salt of iloperidone in the treatment of at least one psychotic symptom in an individual, the method comprising: determining the individual's genotype at locus polymorphism of a single nucleotide ( SNP) rs11851892; and in case the genotype of the individual at the SNP locus is non-GG rs11851892, predict the treatment of the individual with iloperidone be effective.