首页> 外国专利> Dendrimers for photodynamic therapy in the form of water-soluble Polyamino acid-based photosensitizer made and preparing method thereof

Dendrimers for photodynamic therapy in the form of water-soluble Polyamino acid-based photosensitizer made and preparing method thereof

机译:水溶性聚氨基酸基光敏剂形式的用于光动力疗法的树枝状聚合物及其制备方法

摘要

The present invention relates to water-soluble polyamino acids; The present invention relates to a water-soluble light-responsive agent in the form of a dendrimer for photodynamic therapy having a form in which a polyamino acid to which a pH-sensitive substance containing a tertiary amine is bonded is bonded to a light- The response agent has better solubility in water than the existing light responsive agent, and the charge can be controlled by the pH change. In particular, it is possible to improve the production efficiency of reactive oxygen species in the aqueous solution, thereby improving the efficiency of excellent photodynamic therapy There are features.
机译:本发明涉及水溶性聚氨基酸。技术领域本发明涉及一种用于光动力疗法的树枝状聚合物形式的水溶性光敏剂,其形式为其中键合有含叔胺的pH敏感物质的聚氨基酸与光结合的形式。响应剂比现有的光响应剂在水中的溶解度更好,并且电荷可以通过pH的变化来控制。特别是可以提高水溶液中活性氧种类的生产效率,从而提高光动力疗法的优良效率。

著录项

  • 公开/公告号KR101578267B1

    专利类型

  • 公开/公告日2015-12-28

    原文格式PDF

  • 申请/专利权人 가톨릭대학교 산학협력단;

    申请/专利号KR20130086539

  • 发明设计人 나건;박우람;이충성;

    申请日2013-07-23

  • 分类号A61K47/42;A61K47/18;A61K47/48;

  • 国家 KR

  • 入库时间 2022-08-21 14:15:26

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