首页> 外国专利> COMPOUND TARGETING FOLATE RECEPTOR OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND COMPOSITION FOR PREVENTING, DIAGNOSING, OR TREATING CANCER CONTAINING SAME AS ACTIVE INGREDIENT

COMPOUND TARGETING FOLATE RECEPTOR OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND COMPOSITION FOR PREVENTING, DIAGNOSING, OR TREATING CANCER CONTAINING SAME AS ACTIVE INGREDIENT

机译:复合目标叶酸受体或其药学上可接受的盐及其组成,以预防,诊断或治疗包含有效成分的癌症

摘要

The present invention relates to a compound targeting a folate receptor or a pharmaceutically acceptable salt thereof. The present invention further relates to a composition for preventing, diagnosing, or treating cancer, containing the same as an active ingredient. According to the compound or the salt thereof, a peptide with an amino acid sequence represented by glycine-glycine-cysteine-glutamate (GGCE) is attached to folate, leading to a specific binding to a cancer cell on which folate receptors are over-expressed. Thus, the compound or the salt thereof can be useful for preventing, diagnosing, or treating cancer.;COPYRIGHT KIPO 2016
机译:本发明涉及靶向叶酸受体的化合物或其药学上可接受的盐。本发明进一步涉及含有作为有效成分的预防,诊断或治疗癌症的组合物。根据该化合物或其盐,将具有以甘氨酸-甘氨酸-半胱氨酸-谷氨酸(GGCE)表示的氨基酸序列的肽附着于叶酸,从而导致与过度表达叶酸受体的癌细胞特异性结合。 。因此,该化合物或其盐可用于预防,诊断或治疗癌症。; COPYRIGHT KIPO 2016

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