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METHOD FOR DIAGNOSING TYPE 1 DIABETES USING AUTOANTIBODY

机译:使用自体抗体诊断1型糖尿病的方法

摘要

The present invention relates to a composition for diagnosing type 1 diabetes, containing a preparation used for measuring the level of autoantibody which binds to eukaryotic translation elongation factor 1α1 (EEF1A1) or ubiquitin-conjugating enzyme 2L3 (UBE2L3). The present invention further relates to a kit for diagnosing type 1 diabetes containing the composition, and to a method for detecting autoantibody binding to EEF1A1 or UBE2L3 so as to provide information required for diagnosis of type 1 diabetes. The use of the autoantibody binding to the EEF1A1 or UBE2L3 provided in the present invention enables specific diagnosis of the presence of type 1 diabetes. Thus, the autoantibody can be widely used for treating diabetes effectively.;COPYRIGHT KIPO 2016
机译:本发明涉及用于诊断1型糖尿病的组合物,其包含用于测量与真核翻译延伸因子1α1(EEF1A1)或遍在蛋白缀合酶2L3(UBE2L3)结合的自身抗体水平的制剂。本发明进一步涉及包含该组合物的用于诊断1型糖尿病的试剂盒,以及用于检测与EEF1A1或UBE2L3结合的自身抗体以便提供诊断1型糖尿病所需的信息的方法。通过使用与本发明提供的EEF1A1或UBE2L3结合的自身抗体,可以特异性诊断1型糖尿病的存在。因此,自身抗体可广泛用于有效治疗糖尿病。; COPYRIGHT KIPO 2016

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