Method of modifying surface of pancreatic islets using PEG synthetic material and pancreatic islets having modified surface using the method

摘要

present invention is 6-arm PEG to the lipid synthesis and gelatin DOPA and DOPA synthesis and lipid is a fat-soluble with the use of porcine pancreatic islet cell surface phospholipid layer is sandwiched between the lipid containing combined to induction and, by a covalent bond between DOPA and SH 6-arm PEG-SH, DOPA, gelatin -DOPA and linear coupling between the PEG-SH by the method for modifying a swine pancreatic islets through the membrane surface is not any processing to pure pancreatic compared to islet pancreatic islets shapes and insulin secretion levels and cell survival sex change does not appear, by this maintenance period, the blood glucose confirmed that rising improve the stability (Stability) and overall survival (viablilty) of pancreatic islets by in pancreatic islet transplantation it can be useful. ;