- Transcription regulating sigma factor SigA-vm and producing method for glycopeptide compounds by overexpressing the sigma factor

摘要

The present invention relates to a method for screening and introducing a gene encoding a SigA-vm protein responsible for transcription of essential genes from a microorganism producing a non-ribosomal peptide-based compound to produce glycopeptides, lipoglycopeptides, and the like Compounds, preferably glycopeptide-based compounds including vancomycin, teicoplanin, balhimycin, and the like, more preferably vancomycin, Lt; RTI ID = 0.0 production. / RTI