首页> 外国专利> Attention deficit hyperactivity disorder model animal method for evaluating prevention and alleviation of attention deficit diseaseand composition comprising nonspecific Ttype calcium channel blocker for prevention and treatment of attention deficit disease

Attention deficit hyperactivity disorder model animal method for evaluating prevention and alleviation of attention deficit diseaseand composition comprising nonspecific Ttype calcium channel blocker for prevention and treatment of attention deficit disease

机译:用于评估预防和减轻注意缺陷疾病的注意缺陷多动障碍模型动物方法以及包含用于预防和治疗注意缺陷疾病的非特异性T型钙通道阻滞剂的组合物

摘要

the present invention is attention deficit hyperactivity model mouse, and it relates to a screening method of the composition for the difficulty concentrating disease prevention and treatment using, the more a particular insert cobalt line on the right side of the frontal lobe animal model useful as attention deficit hyperactivity model mouse, by administering one of ETO succinate imide of non-specific T- type calcium channel inhibitor in the animal model, brain waves, hyperactivity of the low frequency characteristics of the attention difficulties, and that the lowering of the function can be observed through the results using a mouse model utilized for attention deficit hyperactivity disorder therapeutic agent concentration and screening, it was confirmed that a useful composition containing a non-specific T- type calcium channel inhibitor in the prevention and treatment of disorders of concentration. ;
机译:本发明是注意力缺陷多动症模型小鼠,其涉及用于集中注意力预防和治疗疾病的组合物的筛选方法,其额叶动物模型右侧的特定钴钴线越多,可用作注意力。缺陷多动症模型的小鼠,通过在动物模型中施用一种非特异性T型钙通道抑制剂的ETO琥珀酰亚胺,脑电波,多动症的注意困难的低频特性,以及可以降低功能通过使用用于注意力缺陷多动障碍治疗剂浓度和筛选的小鼠模型的结果观察到的结果,证实了包含非特异性T型钙通道抑制剂的有用组合物可用于预防和治疗浓度障碍。 ;

著录项

  • 公开/公告号KR101625575B1

    专利类型

  • 公开/公告日2016-06-13

    原文格式PDF

  • 申请/专利权人 한국과학기술원;

    申请/专利号KR20130030332

  • 发明设计人 김정진;김대수;

    申请日2013-03-21

  • 分类号A01K67/027;A61B5/0476;A61P25/00;G01N33/15;

  • 国家 KR

  • 入库时间 2022-08-21 14:12:28

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