TRPM8 SULFONAMIDE COMPOUNDS HAVING TRPM8 ANTAGONISTIC ACTIVITY

摘要

Thereby providing a sulfonamide compound having TRPM8 antagonistic activity. A sulfonamide compound of formula (I) or a pharmaceutically acceptable salt thereof, or a prodrug thereof: [Wherein, Ring A is (a) pyridine condensed with benzene; Or (b) a bicyclic aromatic heterocycle consisting of pyridine condensed with a monocyclic aromatic heterocycle, wherein ring A is bonded to the sulfonylamino moiety on the carbon atom adjacent to the nitrogen atom of the pyridine ring making up ring A, Ring B is (a) a monocyclic or bicyclic aromatic hydrocarbon; (b) monocyclic or bicyclic alicyclic hydrocarbons; (c) a monocyclic or bicyclic aromatic heterocycle; Or (d) a monocyclic or bicyclic non-aromatic heterocycle, Ring C is (a) benzene; Or (b) a monocyclic aromatic heterocycle, and Other symbols are the same as defined in the specification].