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Pharmaceutical composition for prevention or treatment of infections caused by biofilm and coating composition for inhibiting formation of biofilm

机译:用于预防或治疗由生物膜引起的感染的药物组合物和用于抑制生物膜形成的包衣组合物

摘要

The present invention provides a pharmaceutical composition for preventing or treating infectious diseases caused by a biofilm, which comprises a pyrimidinedione derivative of the following formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient: [Chemical Formula 1] . The pharmaceutical compositions and coating compositions according to the present invention have excellent antimicrobial effects and show excellent efficacy in suppressing and eliminating biofilm formation. They are useful for preventing or treating various infectious diseases caused by biofilm, And can be effectively used in coating compositions for inhibiting biofilms formed on medical materials, medical implants and the like.
机译:本发明提供了一种用于预防或治疗由生物膜引起的感染性疾病的药物组合物,其包含下式(1)的嘧啶二酮衍生物或其药学上可接受的盐作为活性成分:[化学式1]。根据本发明的药物组合物和包衣组合物具有优异的抗微生物作用,并且在抑制和消除生物膜形成方面显示出优异的功效。它们可用于预防或治疗由生物膜引起的各种感染性疾病,并且可有效地用于抑制在医疗材料,医疗植入物等上形成的生物膜的涂料组合物中。

著录项

  • 公开/公告号KR101670281B1

    专利类型

  • 公开/公告日2016-10-28

    原文格式PDF

  • 申请/专利权人 고려대학교 산학협력단;

    申请/专利号KR20140145684

  • 发明设计人 송재준;

    申请日2014-10-27

  • 分类号A61K31/506;A01N43/62;A61K31/513;A61K47;

  • 国家 KR

  • 入库时间 2022-08-21 14:11:43

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