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SODIUM DEOXYRIBONUCLEATE SUPPOSITORIES, RECTAL AND VAGINAL

机译:脱氧核糖核酸栓剂,直肠和阴道

摘要

FIELD: pharmaceutics.;SUBSTANCE: described is a pharmaceutical composition in form of a suppository, rectal or vaginal characterised by the fact that it contains as an active substance sodium salt of deoxyribonucleic acid and lipophilic base. Said base contains cocoa butter or cocoa butter alloys with paraffin or wax, or hydrogenated fat or vegetable and animal hydrogenated fats, or solid fat in the form of a mixture of lauric acid mono-, di- and triglycerides, or lanol, or alloys hydrogenated fats with wax or a solid paraffin at specified ratio. Also described is a method for preparing the composition.;EFFECT: invention provides high stability during storage at maintaining sufficient bioavailability for effective action.;3 cl, 3 tbl, 5 ex
机译:领域:描述了一种栓剂,直肠或阴道形式的药物组合物,其特征在于它含有脱氧核糖核酸和亲脂性碱的钠盐作为活性物质。所述基料包含可可脂或可可脂与石蜡或蜡的合金,或氢化脂肪或植物和动物的氢化脂肪,或月桂酸甘油一酸酯,甘油二酸酯和甘油三酸酯或羊毛脂的混合物形式的固体脂肪,或氢化的合金含蜡或固态石蜡的特定比例的脂肪。还描述了制备该组合物的方法。效果:本发明在储存期间提供高稳定性,同时保持足够的生物利用度以发挥有效作用。3 cl,3 tbl,5 ex

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