AGENT FOR SEDATING RESPONSE TO EXTERNAL STIMULATION IN SKIN AND METHOD FOR SEDATING THAT RESPONSE TECHNICAL FIELD

摘要

An object of the present invention is to provide an agent for sedating the response of skin to external stimulation. The aforementioned object was achieved by finding a component that promotes CD39 gene expression in Langerhans cells. More specifically, the present invention is based on the finding that the combination of carboxymethyl-beta glucan or a salt thereof polyoxyethylene (POE)/polyoxypropylene (POP) random copolymer dimethyl ether and rosewater promotes CD39 gene expression.