首页> 外国专利> A METHOD FOR PRODUCING A MINOR GINSENOSIDE USING A GINSENOSIDE GLYCOSIDASE

A METHOD FOR PRODUCING A MINOR GINSENOSIDE USING A GINSENOSIDE GLYCOSIDASE

机译：一种利用人参皂苷糖苷酶生产微量人参皂苷的方法

页面导航

摘要
著录项
相似文献

摘要

Provided are a method of producing minor ginsenosides using a ginsenoside glycosidase protein derived from a Microbacterium sp. (Microbacterium testaceum) microorganism, and a composition including the protein for conversion into minor ginsenosides. The ginsenoside glycosidase exhibits very excellent activity of specifically hydrolyzing a sugar at the C-6 position of ginsenoside to convert the ginsenoside into in-vivo absorbable minor ginsenoside, thereby being very usefully applied to mass-production of ginsenoside.

机译：提供了一种使用源自 Microbacter sp。（ Microbacterium testaceum ）微生物的人参皂苷糖苷酶蛋白生产次要人参皂苷的方法，以及包括该蛋白质的用于转化为次要人参皂苷的组合物。人参皂苷糖苷酶显示出非常优异的活性，即特异性地水解人参皂苷C-6位上的糖，将人参皂苷转化为体内可吸收的次要人参皂苷，从而非常有用地应用于人参皂苷的批量生产。 展开▼

著录项

公开/公告号EP3181695A1

专利类型

公开/公告日2017-06-21

原文格式PDF

申请/专利权人 INTELLIGENT SYNTHETIC BIOLOGY CENTER;
展开▼

申请/专利号EP20160175888

发明设计人 KIM SUN CHANG;IM WAN TAEK;CUI CHANG HAO;
展开▼

申请日2016-06-23

分类号C12P33;C12N9/42;

国家 EP

入库时间 2022-08-21 14:03:46

相似文献

专利

外文文献

中文文献

1. 利用人参皂苷糖苷酶的次要人参皂苷的制备方法 [P] . 中国专利： CN106893755A . 2017-06-27

2. 包含高温α-L-阿拉伯呋喃糖苷酶的用于生产人参皂苷化合物K的组合物及制备人参皂苷化合物K的方法 [P] . 中国专利： CN110325648A . 2019-10-11

3. A METHOD FOR PRODUCING A MINOR GINSENOSIDE USING A GINSENOSIDE GLYCOSIDASE [P] . 欧洲知识产权局专利： EP3181695B1 . 2019-11-13

机译：一种利用人参皂苷糖苷酶生产微量人参皂苷的方法

4. Method for producing a minor ginsenoside using a ginsenoside glycosidase [P] . 美国专利： US9926585B2 . 2018-03-27

机译：用人参皂苷糖苷酶生产次要人参皂苷的方法

5. Ginsenoside glycosidase derived from Pseudonocardia sp. and method for producing minor ginsenosides with the same [P] . 韩国专利： KR101733610B1 . 2017-05-10

机译：人参皂苷糖苷酶衍生自假性心包菌。和生产相同的次要人参皂苷的方法

1. High efficiency production of ginsenoside compound K by catalyzing ginsenoside Rb1 using snailase [J] . Zhiguang Duan, Chenhui Zhu, Jingjing Shi, 中国化学工程学报（英文版） . 2018,第007期

2. Ginsenoside Rg1 and Resveratrol Alleviate Acute Kidney Injury Induced by Cisplatin via Downregulation of Autophagy in Mice [J] . Yu Liu, Jiao Qiu, Ruiqiao Tan, 长江医药（英文） . 2021,第001期

3. Enrichment of the less polar ginsenoside (Rg3) from ginseng grown in New Zealand by post-harvest processing and extraction [J] . Wei Chen, Wen-Liang Xu, Dan-Xia Shi, 传统医学研究（英文版） . 2021,第004期

4. Bioconversion of major ginsenosides Rg(1) to minor ginsenoside F-1 using novel recombinant ginsenoside hydrolyzing glycosidase cloned from Sanguibacter keddieii and enzyme characterization [J] . Kim Jin-Kwang, Cui Chang-Hao, Yoon Min-Ho, Journal of Biotechnology . 2012,第3期

5. Enzymatic transformation of the major ginsenoside Rb2 to minor compound Y and compound K by a ginsenoside-hydrolyzing beta-glycosidase from Microbacterium esteraromaticum. [J] . Lin-Hu Quan, Yan Jin, Chao Wang, Journal of industrial microbiology & biotechnology . 2012,第10期

6. Diversity of cultivable beta -glycosidase-producing micro-organisms isolated from the soil of a ginseng field and their ginsenosides-hydrolysing activity. [J] . Fu Y., Yin Z., Wu L., Letters in Applied Microbiology . 2014,第2期

7. A Novel Method for Preparing the Surface Molecularly Imprinted Polymers to Target Isolate Ginsenoside Rg1 and Its Analogues [C] . Qingshan Liu, Una Yi, Qiujuan Wang International Conference on Advanced Engineering Materials and Technology . 2011

8. Genome Sequencing of Panax notoginseng Reveals Genes Involved in Ginsenoside Biosynthesis and Disease Resistance [D] . Fan, Guangyi. 2019

9. Enhanced production of ginsenoside Rh2(S) from PPD-type major ginsenosides using BglSk cloned from Saccharibacillus kuerlensis together with two glycosidase in series [O] . Muhammad Zubair Siddiqi, Hipolito Amaral Ximenes, Bong-Kyu Song, 2021

10. Diversity of cultivable β -glycosidase-producing micro-organisms isolated from the soil of a ginseng field and their ginsenosides-hydrolysing activity [O] . Y. Fu, Z. Yin, L. Wu, 2013

1. Ginsenoside Rb1 produces antidepressant-like effects in chronic social defeat stress model of depression through BDNF-TrkB sig⁃naling pathway [J] . JIANG Ning ,HUANG Hong ,ZHANG Yi-wen . 中国药理学与毒理学杂志 . 2021,第9期

2. Enrichment of the less polar ginsenoside (Rg3) from ginseng grown in New Zealand by post-harvest processing and extraction [J] . Wei Chen ,Wen-Liang Xu ,Dan-Xia Shi . 传统医学研究（TMR） . 2021,第004期

3. 拟青霉菌一种人参皂苷β-葡萄糖苷酶的分离纯化及其酶学特性 [C] . 严钦 ,周伟 ,李幸慰 . 2007年全国生化与生物技术药物学术年会 . 2007

4. 糖苷酶的筛选、组合及固定化生产稀有人参皂苷Rh2的研究 [A] . 曹领改 . 2020