METHOD FOR PRODUCING SOLUBLE PHOSPHORYLATED CHITIN OR SOLUBLE PHOSPHORYLATED COLLAGEN, METHOD FOR PRODUCING COMPOSITE OF PHOSPHORYLATED CHITIN OR PHOSPHORYLATED COLLAGEN AND TITANIUM, METHOD FOR PRODUCING POLYURETHANE FOAM, COMPOSITE, METHOD FOR PRODUCING PHOSPHORYLATED COLLAGEN, AND METHOD FOR PRODUCING COMPOSITE OF PHOSPHORYLATED COLLAGEN AND TITANIUM

摘要

PROBLEM TO BE SOLVED: To provide a method of solubilization by phosphorylating an insoluble biological macromolecule, particularly chitin and collagen.SOLUTION: Chitin and collagen can be phosphorylated and made soluble by: suspending chitin or collagen in a particular dispersion medium; phosphorylating the suspended chitin or collagen in the presence of a catalyst; and separating the phosphorylated chitin or collagen. Said particular dispersion medium is an aprotic solvent when phosphorylating chitin or insoluble collagen and is a phosphate buffer solution having a concentration of 0.5 mol/L or more and 1.0 mol/L or less when phosphorylating collagen.SELECTED DRAWING: Figure 2