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ENGINEERED NUCLEIC ACID AND METHOD OF USE THEREOF FOR NON-HUMAN VERTEBRATE

机译:工程化的核酸及其用于非人类脊椎动物的方法

摘要

PROBLEM TO BE SOLVED: To provide a formulation, composition, kit, and method for delivering a biological moiety, such as a modified nucleic acid, into a cell to induce, reduce or modulate protein expression in a non-human vertebrate.SOLUTION: According to the present invention, a method of producing a polypeptide of interest in a cell of a non-human vertebrate subject in need thereof comprises administering to the subject a pharmaceutical composition comprising a nucleic acid encoding the polypeptide of interest.SELECTED DRAWING: None
机译:要解决的问题:提供用于将生物部分(例如修饰的核酸)递送到细胞中以诱导,减少或调节非人类脊椎动物中蛋白质表达的制剂,组合物,试剂盒和方法。对于本发明,一种在需要其的非人类脊椎动物受试者的细胞中产生目标多肽的方法包括向该受试者施用包含编码该目标多肽的核酸的药物组合物。

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