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Imidazothiadiazole derivatives as protease-activated receptor 4 (PAR4) inhibitors for the treatment of platelet aggregation

机译:咪唑并噻二唑衍生物作为蛋白酶激活受体4(PAR4)抑制剂,用于治疗血小板聚集

摘要

The present invention provides imidazothiadiazole compounds of Formula (I) wherein A, B, D, Rx, R1, R2, R3, X1, X2 and s are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments.
机译:本发明提供了式(I)的咪唑并噻二唑化合物或其立体异构体,互变异构体,药学上可接受的盐或溶剂合物形式,其中A,B,D,Rx,R1,R2,R3,X1,X2和s如本文所定义。其中所有变量均如本文所定义。这些化合物是血小板聚集的抑制剂,因此可以用作药物。

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