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Imidazothiadiazole and imidazopyridazine derivatives as protease-activated receptor 4 (PAR4) inhibitors for the treatment of platelet aggregation
Imidazothiadiazole and imidazopyridazine derivatives as protease-activated receptor 4 (PAR4) inhibitors for the treatment of platelet aggregation
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机译:咪唑并噻二唑和咪唑并哒嗪衍生物作为蛋白酶激活受体4(PAR4)抑制剂,用于治疗血小板聚集
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摘要
The present invention provides imidazothiadiazole compounds of Formula (I); Wherein W, Y, R0, R2, R4, Ra, Rb, X1, X2, X3 and X4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.
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