NEXT GENERATION RNA-SEQUENCING AND LONG NON-CODING RNA IN GLIOBLASTOMA MULTIFORME

摘要

LncRNAs are emerging as important oncogenic drivers in many cancers, but comprehensive, agnostic studies to identify key lncRNAs involved in GBM are lacking. Described herein are new lncRNA involved in gliomagenesis and prognosis, elucidating the biological functions of these relatively unknown biological actors and opening new therapeutic avenues for therapeutic development.