首页>
外国专利>
PREPARATION OF pH-RESPONSIVE NANOPARTICLES AND PROMOTED DELIVERY OF ANTICANCER DRUGS INTO DEEP TUMOR TISSUES AND APPLICATION THEREOF
PREPARATION OF pH-RESPONSIVE NANOPARTICLES AND PROMOTED DELIVERY OF ANTICANCER DRUGS INTO DEEP TUMOR TISSUES AND APPLICATION THEREOF
展开▼
机译:pH敏感纳米颗粒的制备及抗癌药物促进体内深部肿瘤的递送及其应用
展开▼
页面导航
摘要
著录项
相似文献
摘要
A pH-responsive nanoparticle made of a pH-responsive polymer and a poly(lactic-co-glycolic acid) by self-assembly includes a polyethylene glycol derivative and a R-Histidine derivative that are subjected to a chemical reaction to form the pH-responsive polymer, wherein the surface electric potential of the pH-responsive nanoparticle is −25 to 10 mV, such that when a pH value of the pH-responsive nanoparticle is changed from 7.4 to 5.0 depending upon an external environment, a surface zeta potential of the pH-responsive nanoparticle is converted from negative charge to positive charge.
展开▼