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ENTERIC-COATED HEMOGLOBIN MULTIPARTICULATE FOR ORAL DELIVERY OF HEMOGLOBIN BASED OXYGEN CARRIERS
ENTERIC-COATED HEMOGLOBIN MULTIPARTICULATE FOR ORAL DELIVERY OF HEMOGLOBIN BASED OXYGEN CARRIERS
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机译:肠溶血红蛋白多颗粒口服血红蛋白载氧体
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摘要
The present invention provides an enteric-coated hemoglobin multiparticulate comprising a core, a hemoglobin formulation coating, an inner or sub-coating, and an enteric coating. The present invention also provides a method of preparing said enteric-coated hemoglobin multiparticulate. The present invention further provides a method for treating various diseases caused by oxygen deficiency comprising administering to a subject said enteric-coated hemoglobin multiparticulate in order to orally deliver the encapsulated hemoglobin-based oxygen carriers to a specific target of said subject in a controlled release manner.
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