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System and method for detecting components of a mixture including a valving scheme for competition assays

机译:用于检测混合物成分的系统和方法,包括用于竞争分析的阀门方案

摘要

Examples are described including measurement systems for conducting competition assays. A first chamber of an assay device may be loaded with a sample containing a target antigen. The target antigen in the sample may be allowed to bind to antibody-coated beads in the first chamber. A control layer separating the first chamber from a second chamber may then be opened to allow a labeling agent loaded in a first portion of the second chamber to bind to any unoccupied sites on the antibodies. A centrifugal force may then be applied to transport the beads through a density media to a detection region for measurement by a detection unit.
机译:描述了示例,包括用于进行竞争测定的测量系统。测定装置的第一腔室可以装载有含有靶抗原的样品。可以允许样品中的靶抗原与第一腔室中的抗体包被的珠子结合。然后可以打开将第一腔室与第二腔室分隔开的控制层,以允许装载在第二腔室的第一部分中的标记剂与抗体上任何未占用的位点结合。然后可以施加离心力以将珠粒通过密度介质传输至检测区域,以通过检测单元进行测量。

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